I've been doing A LOT of learning online lately. Reading, researching, etc. trying to become One With XML. I've discovered that by bumping up many articles in Mozilla to 120% or even 150% my reading comprehension goes up by a similar amount (even though the amount of text on the screen decreases most of the time).
Being a Geek, I'd really like to use all the real estate on my screen, but I can literally FEEL the difference when trying to grok a web page with small fonts vs. big fonts. The former doesn't really get all the way to the back of my brain (where the little man with a pencil jots down notes for later), but the big fonts do.
Time for a bigger screen I think.